Christoph Dehio, Maximiliano Gutierrez, Deborah Hung, Tanja Schneider
June 9-13, 2024
Ascona, Switzerland
Over the past decades, pan-resistant strains of major bacterial pathogens have emerged rendering available antibiotics ineffective and putting at risk many achievements of modern medicine. New ways to identify clinically effective antimicrobials are urgently needed. However, the current antimicrobial development pipeline is inadequate because of high attrition and limited coverage of multi-drug resistant Gram-negative bacteria.
This conference aligns with the scope of the National Center of Competence in Research “AntiResist” which aims at revitalizing antibiotic discovery by bringing a patient-centered paradigm shift. Such a shift requires a multidisciplinary approach starting at the bedside. Many factors affect the development of novel antibiotics such as our limited understanding of the physiology and heterogeneity of bacterial pathogens in patients and their interactions with microbiota. Bacteria growing in patients experience environments that are very different from standard laboratory conditions traditionally used for antibacterial discovery.
This conference will review the current knowledge of:
- Clinical relevance of antibiotic resilience
- Axenic model systems and single cell technologies
- Complex tissue model systems
- Drug penetrance and action through scale
- New approaches in antibiotic discovery and development
- Non-traditional antibacterials
It will introduce students to emerging concepts that promise to accelerate antibacterial discovery, improve treatment regimens and uncover novel targets for eradicating pathogens.
It will bring together world-leading clinicians, microbiologists, tissue engineers and chemists who share common interests in the field and work towards the development of urgently needed control strategies to win the race against superbugs.
For more information visit the conference website. For specific questions regarding the registration or financial assistance, contact info@nccr-antiresist.ch
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