How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups, high-end core facilities and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!
The FACS Core Facility (FCF) provides extensive flow cytometry services in collaborative setting, empowering researchers to achieve their scientific goals. The FCF supports all Biozentrum researchers as well as the larger Basel community.
We seek an individual with flow cytometry background who is eager to work in a dynamic, diverse and innovative environment. This is a joint position with the Biozentrum (60%) and the Institute of Molecular and Clinical Ophthalmology Basel (20%).
Responsibilities include:
The BZ FCF currently operates 3 high-speed cell sorters: BD FACSAriaFusion, BD FACSAriaIII, BD FACSMelody and 3 analyzers: BD LSRFortessa, BD FACS CantoII and Cytek Amnis ImageStreamx MK II. We also have Bucher Bio Singulator S100 tissue dissociation, Oxford Nanopore Sequencing and 10x Chromium X platform.
We are looking for an enthusiastic person with a minimum Bachelor or Master degree in Cell Biology, Molecular Biology or Immunology or equivalent experience. Previous experience with flow cytometry, cell sorting and/or flow cytometry data analysis is desirable. The ideal candidate is service oriented, proactive and an excellent team player, working to implement and evaluate new instruments and software, and who fosters collaboration across disciplines. We collaborate with neighbouring flow core facilities and across Switzerland, excellent social skills and communication skills in English are essential.
The Biozentrum offers a cutting-edge research infrastructure, a highly international environment and excellent working conditions: Access to sports programs and fitness facilities, well-established services for balancing career and family (e.g. childcare, modern parenthood regulations and more) and numerous courses for training and development. The University of Basel is an equal opportunity employer and encourages applications from all identities and backgrounds. The position is initially for 2 years with the possibility of further extension. Salary and benefits according to University of Basel standards.
Basel is a vibrant international city, home to people from 150 nations. Situated at the crossroads of Switzerland, Germany, and France, it stands as Europe’s leading life sciences hub. The city offers a high quality of life and a diverse, dynamic cultural scene.
Please apply online with a CV, letter of motivation, and the name/address of two references. Please note that only online-applications will be accepted.
Review of applications will start immediately and proceed until the position has been filled. Early application is strongly encouraged.
For further information, please feel free to contact Stella Stefanova, Head of FACS Core Facility, +41 61 207 21 56, stella.stefanova@unibas.chHow does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!
We are looking for an administrative assistant for two research groups.We are looking for a person who enjoys supporting and thereby enabling modern research as a member of a scientific team. Do you work in a goal-oriented, forward-looking and prudent manner, are a team player, reliable, well organized and used to working independently on a defined project? Do you react confidently and flexibly to the diverse demands of the university research environment? Do you enjoy interacting with people from all over the world? Then you are the person we are looking for.
Please apply online with a CV, letter of motivation, reference letters if available to you, and the name/address of at least two references for contact. Review of applications will start immediately and continue until the position is filled. Please note that only online applications via the application portal will be accepted.
For any informal enquiries, please contact Manuela Holzer, HR Biozentrum, 061 207 20 22, manuela.holzer@unibas.ch.How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. is one of the world’s leading life sciences institutes. With 33 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!
In Prof. Torsten Schwede's group, we use computational methods, with a strong focus on artificial intelligence, for integrative modelling of macromolecular complexes, including protein assemblies, protein-ligand interactions, and conformational changes. Our research also aims to understand and predict protein-protein complementarity, design artificial protein binders, investigate the effects of mutations on protein structure and function, and apply protein representation learning to uncover hidden links in the "dark" proteome.
At the SIB Swiss Institute of Bioinformatics, we develop SWISS-MODEL (https://swissmodel.expasy.org), a widely used web-based platform for generating high-accuracy 3D models of protein structures and complexes for application in life sciences. In addition, we develop and maintain PLINDER, a resource designed to drive breakthroughs in deep learning-based protein-ligand complex prediction, as well as the Protein Universe Atlas, an interactive web resource for exploring the vast landscape of publicly available protein sequence and structure data. We also organise community efforts to advance the state of the art in structure prediction through initiatives such as CASP and CAMEO.
We are seeking a senior postdoctoral researcher to join our dynamic team. This position offers a unique opportunity for an ambitious scientist, providing the freedom to develop own research directions as part of our group's broader scientific efforts. We encourage candidates to explain in their cover letter how their scientific background and interests complement our group’s research.
The position is initially funded for 3 years. Our team and the interactive, highly innovative nature of the Biozentrum and of Life Science in Basel provide a stimulating environment that offers all the possibilities to be creative and highly productive. Basel is a city that provides a high standard of living and offers all the advantages of an international community.
Please apply online and provide a motivation statement that describes how your background and scientific interests complement our group’s research efforts, CV, and contact information for two references.
Review of applications will begin immediately and proceed until the position has been filled. Early application is strongly encouraged.
How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups, high-end core facilities and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!
Skilled and motivated individuals are encouraged to apply for a 4-year PhD project in the research group of Roderick Lim at the Biozentrum, University of Basel, Switzerland.
The Lim Lab is interested in understanding how biological nuclear pore complexes (NPCs) regulate selective transport processes and how this functionality can be leveraged in the design of bio-inspired artificial nanopores. In this project, we want to apply high-speed atomic force microscopy (HS-AFM), and other super-resolution microscopies, to resolve the intermolecular forces at play within NPCs and artificial “NPC-like” nanopores.
Besides basic research, PhD candidates will also have to contribute to undergraduate level teaching.
Interested candidates should have a background in experimental physics, biophysics, nanoscience, physical chemistry, materials science or related disciplines. Strong candidates will have experience in AFM, and/or HS-AFM. Familiarity with Jacob Israelachvili’s classic textbook “Intermolecular and Surface Forces” is a plus. The ideal candidate should be highly interactive and capable of independent research in a team environment. A solid command of oral and written English is essential.
We are a multi-national, interdisciplinary lab that combines biophysical, molecular and cellular approaches to investigate intriguing biological problems. The successful applicant will benefit from a highly stimulating, collaborative research environment as well as state-of-the-art infrastructure and facilities at the new Biozentrum research tower.
Basel is an international city with people from 150 nations. Located on the border where three countries meet - Switzerland-Germany-France - it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.
The application should include a brief personal statement, explaining how your qualifications and experience make you a good candidate for this job, together with a full, up-to-date CV, diplomas and 3 reference letters.
Review of applications will start immediately and continue until the position is filled. Please note that only online applications via the application portal will be accepted.
For further information, please contact stephanie.gehlen@unibas.chHow does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups, high-end core facilities and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!
We are seeking a highly motivated Scientist/Research Associate to join our team at the Proteomics Core Facility (PCF). The PCF provides state-of-the-art proteomic techniques to support life science research at the Biozentrum and other Basel University institutes. It is tightly integrated in an internationally leading scientific surrounding. The main focus of the group is the development of new data-independent mass spectrometric workflows for sensitive, quantitative protein and post-translational modification profiling and their integration in interdisciplinary biological projects.
The primary responsibilities for this position will include the operation and maintenance of latest LC-MS systems (Vanquish Neo, EvoSep, Exploris 480, Eclipse, timsTOF Ultra 2), the assistance and teaching of researchers performing proteomics analyses and general lab management. Duties will include supervising sample preparation, analyzing samples by quantitative and sensitive LC-MS/MS (SWATH-MS), data analysis via a suite of software tools, continuing analytical method development and reporting of results to collaborators on a regular basis, including internal presentations.
The ideal candidate should have proof of proficiency in LC-MS based proteomics techniques, including planning of experiments, sample preparation, operation of LC-MS platforms, data analysis software tools and practical experience in organizing a laboratory. Prior experience with the preparation and analysis of low input samples and data-independent workflows would be advantageous. The successful candidate should be highly organized, detail-oriented and computer literate. The candidate should have good written and verbal communication skills, be able to work both independently and within a team and have a MS degree or higher in a biology or chemistry related subject with 2+ years of experience. High proficiency in spoken and written English is required.
The position offers a challenging opportunity to join a growing and rapidly evolving bioanalytical field and to join a team of highly motivated scientists. Access to sports programs and fitness facilities, well-established services for balancing career and family (e.g. childcare, modern parenthood regulations and more) and numerous courses for training and development. The position is initially for 2 years, with the possibility of further extension for 4 years after positive evaluation. Salary and benefits according to University of Basel standards.
The application should include a brief personal statement, explaining how your qualifications and experience make you a good candidate for this job, together with a full, up-to-date CV and addresses of 2 references.
We start reviewing applications from 15 March 2025 until the position is filled. In all cases, you will be notified of the outcome of your application. Please note that only online applications via the application portal will be accepted.
For further information, please contact Dr. Alexander Schmidt, Head of Proteomics Core Facility, +41 61 207 20 59, alex.schmidt@unibas.ch