BIPED Application Portal

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

The Keller Valsecchi group explores the epigenetic mechanisms and physiological relevance of gene dosage in regulating cellular function in male and female animals - from individual genes to chromosome-wide scales. We are looking for someone that helps our group understanding the molecular mechanisms governing the regulation of sex chromosomes in non-model organisms.

Responsibilities

• Collaborate with team members to support scientific research projects by performing experiments and developing protocols.
• Actively participate in our research team, working closely with the group leader, undergraduates, PhD students, and postdocs.
• Assist with the practical training of undergraduate students.

Your profile

Essential Qualifications

• MSc. degree in Life Sciences or a degree as a laboratory technician.
• Experience in an academic research lab.
• Hands-on knowlege in at least one of the following areas: Imaging: Sample preparation (whole mount and/or sections/histology) and fluorescence microscopy (epifluorescence/confocal); Genomics: Techniques such as ChIP-seq, CUT&Tag, RNA-seq, library preparation for deep sequencing.

Any of the following qualification or interests would be an asset

• Experience or interest rearing or working with non-model or emerging model organisms.
• Knowledge of image analysis software like Fiji, Imaris, or Zen Blue.
• Drosophila genetics.
• Understanding of the academic publishing process.

Key Competencies

• Organized and systematic personality with the ability to work independently.
• Ability to perform experiments reproducibly, ensuring consistency and reliability in wet lab procedures and documentation of data.
• Team player capable of effectively communicating in a culturally diverse, international environment and across disciplines (e.g. with bioinformaticians).
• Fluent in German and English (working language) and proficient in Microsoft Office applications (Word, Power Point, Excel, etc.).
• Enthusiasm for contributing to a multidisciplinary scientific environment exploring diverse topics, from basic biology to disease-relevant areas.

What we offer

• Access to a modern, well-equipped working environment at the Biozentrum.
• A collaborative work environment with flat hierarchies.
• Support for professional development and career advancement, opportunities to acquire new skills
• The position is financed by third party funding and thus fixed-term for two years. Salary and benefits according to University of Basel standards.

Application / Contact

The application should include a brief personal statement, explaining how your qualifications and experience relate to the role, together with a full, up-to-date CV, diplomas and two reference letters. Review of applications will start immediately and proceed until the position is filled. Only online applications will be considered.

Starting Date: January 2026 or by agreement

The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

The Jenal Lab at the Biozentrum of the University of Basel is seeking a highly motivated and skilled postdoc with expertise in molecular biology, biochemistry and/or structural biology to join our team. This position offers an exciting opportunity to contribute to cutting-edge research in structure-based discovery of anti-biofilm compounds.

Our research group at the Biozentrum is embedded in the National Centre of Competence in Research (NCCR) AntiResist. We develop and use state-of-the-art organoid technology to better understand human infections and foster antibiotic discovery. We conduct a wide range of assays including cellular and molecular microbiology, advanced microscopy, omics etc. to reach a detailed understanding of human infections, host response and drug treatment.

The project

The project aims to develop novel anti-biofilm compounds that can be used to treat biofilm-related infections caused by a range of bacterial pathogens. Based on structural data demonstrating how an existing anti-biofilm compound binds to and activates its specific target in Pseudomonas aeruginosa, we will design, develop and test novel anti-biofilm compounds with broader activity against the WHO priority pathogens Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii. You will be working in a trans-national research consortium including experts in structure-based modelling, structure biology and chemistry.

Your profile

PhD in Molecular Biology, Microbiology, Biochemistry or Structural Biology with research experience in any of these areas. You are highly motivated, organized, independent, flexible, with excellent communication and strong team-player skills.

We offer

This position offers an exciting opportunity for a highly motivated individual to contribute to a vibrant international research community and to tackle challenging questions in infection biology and drug development. The Biozentrum is a front-line international research environment with cutting-edge research infrastructure and excellent working conditions. The position is initially for one year, with the possibility of further extension. Salary and benefits according to University of Basel standards.

Basel is an international city with people from 150 nations. Located on the border where three countries meet, Switzerland-Germany-France, it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.

Application / Contact

Please apply online.

The application should include a brief personal statement, explaining how your qualifications and experience relate to the role, together with a full, up-to-date CV, diplomas and two reference letters. Review of applications will start immediately and proceed until the position is filled. Only online applications will be considered.

Starting Date: As soon as possible

The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

The Jenal Lab at the Biozentrum of the University of Basel is seeking a highly motivated and skilled postdoc with expertise in molecular biology, microscopy and/or phage biology to join our team. This position offers an exciting opportunity to contribute to cutting-edge research at the interface of bacterial signal transduction and phage biology.

Our research group at the Biozentrum is embedded in the National Centre of Competence in Research (NCCR) AntiResist. We develop and use state-of-the-art organoid technology to better understand human infections and foster antibiotic discovery. We conduct a wide range of assays including cellular and molecular microbiology, advanced microscopy, omics etc. to reach a detailed understanding of human infections, host response and drug treatment.

The project

The aim of the project is to understand the role of the second messenger c-di-GMP in E. coli bacteriophage infection and propagation and to investigate mechanisms that allow the host to escape phage killing by modulating its own signal transduction pathways. You will be working in a dynamic team of researchers with broad expertise in molecular biology, microbiology and infection biology and you will be interacting with researcher from neighboring disciplines like structural biology or computational biology.

Your profile

You have a PhD in Molecular Biology, Microbiology, Biochemistry or related fields with research experience in any of these areas. You are highly motivated, organized, and flexible. You have good communication skills and you are able to work both independently and in a team with other researchers.

We offer

This position offers an exciting opportunity for a highly motivated individual to contribute to a vibrant international research community and to tackle challenging questions in infection biology and drug development. The Biozentrum is a front-line international research environment with cutting-edge research infrastructure and excellent working conditions. The position is initially for one year, with the possibility of further extension. Salary and benefits according to University of Basel standards.

Basel is an international city with people from 150 nations. Located on the border where three countries meet, Switzerland-Germany-France, it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.

Application / Contact

Please apply online.

The application should include a brief personal statement, explaining how your qualifications and experience relate to the role, together with a full, up-to-date CV, diplomas and two reference letters. Review of applications will start immediately and proceed until the position is filled. Only online applications will be considered.

NCCR AntiResist aims to train the next generation of researchers and clinicians in infectious diseases using novel interdisciplinary approaches. To support this aim, NCCR AntiResist awards unique PhD Fellowships in Antibiotic Discovery.

We invite talented and ambitious young scientists from all over the world to join our NCCR AntiResist community. Our fellowships are particularly well suited for students from the three major research fields of the NCCR AntiResist: clinical research, infection biology and engineering.

NCCR AntiResist aims to train the next generation of researchers and clinicians in infectious diseases using novel interdisciplinary approaches. To support this aim, NCCR AntiResist is awarding a unique, annual Research Fellowship in Infection and Treatment for Clinicians.

The Research Fellowship for Clinicians supports career development in academic medicine, educates the next generation of clinicians in areas relevant to infection and treatment, and fosters the growth of clinician-scientists committed to bridging clinical practice and basic research. It aims to strengthen the translational bridge between basic science and clinical practice within the framework of NCCR AntiResist. Further information about the role can be found on our website.

We invite talented and ambitious young clinicians with an interest in basic and translational infectious disease research to join our NCCR AntiResist community.