How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups, high-end core facilities and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!
Skilled and motivated individuals are encouraged to apply for a 4-year PhD project in the research group of Roderick Lim at the Biozentrum, University of Basel, Switzerland.
The Lim Lab is interested in understanding how biological nuclear pore complexes (NPCs) regulate selective transport processes and how this functionality can be leveraged in the design of bio-inspired artificial nanopores. In this project, we want to apply high-speed atomic force microscopy (HS-AFM), and other super-resolution microscopies, to resolve the intermolecular forces at play within NPCs and artificial “NPC-like” nanopores.
Besides basic research, PhD candidates will also have to contribute to undergraduate level teaching.
Interested candidates should have a background in experimental physics, biophysics, nanoscience, physical chemistry, materials science or related disciplines. Strong candidates will have experience in AFM, and/or HS-AFM. Familiarity with Jacob Israelachvili’s classic textbook “Intermolecular and Surface Forces” is a plus. The ideal candidate should be highly interactive and capable of independent research in a team environment. A solid command of oral and written English is essential.
We are a multi-national, interdisciplinary lab that combines biophysical, molecular and cellular approaches to investigate intriguing biological problems. The successful applicant will benefit from a highly stimulating, collaborative research environment as well as state-of-the-art infrastructure and facilities at the new Biozentrum research tower.
Basel is an international city with people from 150 nations. Located on the border where three countries meet - Switzerland-Germany-France - it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.
The application should include a brief personal statement, explaining how your qualifications and experience make you a good candidate for this job, together with a full, up-to-date CV, diplomas and 3 reference letters.
Review of applications will start immediately and continue until the position is filled. Please note that only online applications via the application portal will be accepted.
For further information, please contact stephanie.gehlen@unibas.chHow does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups, high-end core facilities and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!
We are seeking a highly motivated Scientist/Research Associate to join our team at the Proteomics Core Facility (PCF). The PCF provides state-of-the-art proteomic techniques to support life science research at the Biozentrum and other Basel University institutes. It is tightly integrated in an internationally leading scientific surrounding. The main focus of the group is the development of new data-independent mass spectrometric workflows for sensitive, quantitative protein and post-translational modification profiling and their integration in interdisciplinary biological projects.
The primary responsibilities for this position will include the operation and maintenance of latest LC-MS systems (Vanquish Neo, EvoSep, Exploris 480, Eclipse, timsTOF Ultra 2), the assistance and teaching of researchers performing proteomics analyses and general lab management. Duties will include supervising sample preparation, analyzing samples by quantitative and sensitive LC-MS/MS (SWATH-MS), data analysis via a suite of software tools, continuing analytical method development and reporting of results to collaborators on a regular basis, including internal presentations.
The ideal candidate should have proof of proficiency in LC-MS based proteomics techniques, including planning of experiments, sample preparation, operation of LC-MS platforms, data analysis software tools and practical experience in organizing a laboratory. Prior experience with the preparation and analysis of low input samples and data-independent workflows would be advantageous. The successful candidate should be highly organized, detail-oriented and computer literate. The candidate should have good written and verbal communication skills, be able to work both independently and within a team and have a MS degree or higher in a biology or chemistry related subject with 2+ years of experience. High proficiency in spoken and written English is required.
The position offers a challenging opportunity to join a growing and rapidly evolving bioanalytical field and to join a team of highly motivated scientists. Access to sports programs and fitness facilities, well-established services for balancing career and family (e.g. childcare, modern parenthood regulations and more) and numerous courses for training and development. The position is initially for 2 years, with the possibility of further extension for 4 years after positive evaluation. Salary and benefits according to University of Basel standards.
The application should include a brief personal statement, explaining how your qualifications and experience make you a good candidate for this job, together with a full, up-to-date CV and addresses of 2 references.
We start reviewing applications from 15 March 2025 until the position is filled. In all cases, you will be notified of the outcome of your application. Please note that only online applications via the application portal will be accepted.
For further information, please contact Dr. Alexander Schmidt, Head of Proteomics Core Facility, +41 61 207 20 59, alex.schmidt@unibas.chHow does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups, high-end core facilities and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!
The Keller Lab of the Biozentrum is seeking a highly motivated and skilled laboratory technician. The Keller lab explores the epigenetic mechanisms and physiological relevance of gene dosage in regulating cellular function in male and female animals - from individual genes to chromosome-wide scales.Applicants should have a degree as a laboratory technician or a degree in Life Sciences and experience in an academic research environment (wet lab experimental work). We expect proficiency in at least one of the following areas (expertise in multiple areas is advantageous but not mandatory).
As an ideal candidate, you are an organized and systematic personality and an excellent team player capable of effectively communicating in a culturally diverse, international environment. Fluent communication skills in German and English are essential. The successful candidate proactive and can work independently in a team environment. Proficiency in Microsoft Office application is required.
This position offers an exciting opportunity for a highly motivated individual to contribute to a vibrant international research community and to conduct own research projects. We have a collaborative work environment with flat hierarchies and a flexible work schedule. There is the possibility of hands-on training in relevant techniques and opportunities to acquire new skills. The Biozentrum is a front-line international research environment with cutting-edge research infrastructure and excellent working conditions.
The position is initially for one year, with the possibility of further extension. Salary and benefits according to University of Basel standards.
The application should include a brief personal statement, explaining how your qualifications and experience relate to the role, together with a full, up-to-date CV, diplomas and the contact details of at least one reference person. Review of applications will start immediately until the position is filled. Please note that only online applications will be considered.
For any informal inquiries, please contact Claudia Keller Valsecchi: c.kellervalsecchi@unibas.chHow does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. is one of the world’s leading life sciences institutes. With 33 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!
We are looking to recruit a highly motivated laboratory technician for an third-party funded project led by Marc van Oostrum in the laboratory of Peter Scheiffele.In an interdisciplinary project we will investigate the molecular trajectories of synaptic proteomes in neurodegenerative disease models (see van Oostrum et. al. 2023 Cell). The project integrates molecular neurobiology with systems neuroscience and combines state-of-the-art mass spectrometry-based proteomics technologies with fluorescence activated sorting and in vivo labelling of defined synaptic populations. We are looking for a highly motivated laboratory technician that is excited to develop new technologies in order to drive biology.
Degree in biology (Bachelor’s/Master’s) or training as a lab assistant/technician with a strong interest in interdisciplinary neurobiology across scales from molecules to circuits. The project involves stereotactic surgery, genome editing methods and primary cell culture. Experience in any of these domains is benefical. The position is funded and salary is according to institutional guidelines.
A project at the frontier of science to solve fundamental questions in neurobiology. You will have the unique opportunity to join a small team with close guidance by the SNF Ambizione project grantee Marc van Oostrum while at the same time being embedded in an internationally leading group of dynamic and collaborative scientists, Phd students, postdocs and technicians.The Biozentrum provides a highly stimulating collaborative research environment with a fantastic infrastructure in a brand-new building, as well as state-of-the-art technology platforms for cutting-edge interdisciplinary research.
Basel is an international city with people from 150 nations. Located on the border where three countries meet – Switzerland, Germany and France – it is Europe’s most important life sciences hub. Basel provides a high standard of living and a rich cultural atmosphere.
The position is initially for 2 years. Salary and benefits according to University of Basel standards.
Applications should include:
Review of applications will start immediately and continue until the position is filled. Only online applications will be considered.
For any informal enquiries, please contact: marc.vanoostrum@unibas.chThe Biozentrum offers Bachelor Students the opportunity to immerse themselves in real-life science projects. During the "Biozentrum Research Summer 2025" you will spend seven to nine weeks in a Biozentrum Research Group, perform original research under the guidance of experienced scientists and participate in an inspiring scientific and social program. The internship is concluded with a written report on your research progresses. By the end of your time in Basel, you will have the chance to present your results to the Biozentrum community as a speaker of the Research Summer Symposium. The internship is open to Bachelor Students in Biology, Nanosciences, Chemistry, Physics, Computational Sciences and related fields. The program is open to students with a Swiss or EU citizenship as well as holders of a Swiss C-permit.