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Currently open positions

Assistant/Associate Professor in Structural Biology, Biological Imaging or Biophysics

The Biozentrum of the University of Basel in Switzerland invites applications for a tenure track assistant professorship or a tenured associate professorship in Structural Biology, Biological Imaging or Biophysics. We encourage applications from candidates who explore fundamental questions in biology ranging from atomic to cellular resolution.

Your position

The successful candidate will have an outstanding research record and strong communication skills, will complement and enhance the research portfolio of the Biozentrum as well as the broader Basel Life Sciences Community, and will contribute to teaching at the undergraduate and graduate level.

We offer

We offer a very generous research endowment and state-of-the art core facilities. The Biozentrum consists of 30 research groups and 250 postdoctoral fellows and graduate students from more than 50 countries researching in fields ranging from structural, computational, cellular and developmental biology to microbiology and neuroscience. The working language in the Biozentrum is English. Basel is the home of a vibrant international life sciences community and provides a high standard of living and a superb cultural and cosmopolitan atmosphere.

Application/Contact

Applications (including a short motivation letter, CV, a list of publications, and a two-page summary of your current and future research) should be addressed to Prof. Dr. Marcel Mayor, Dean of the Faculty of Science and submitted online as one single PDF. During online submission applicants are asked to request three referees to submit confidential letters of reference.

Requests for further information may be addressed to Prof. Dr. Alex Schier (alex.schier@unibas.ch). If your question is about the online application process, please contact the Office of the Dean (dekanat-philnat@unibas.ch).

The deadline for receipt of applications is September 30, 2024. The University of Basel is an equal opportunity and family-friendly employer committed to excellence through diversity.

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IT Support Specialist Proteomics (100%)

Starting immediately or upon agreement

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups, high-end core facilities and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

We are looking to recruit a self-motivated IT Support Specialist Proteomics to join our team at the Proteomics Core Facility (PCF). The PCF provides state-of-the art proteomic methodologies to support life science research at the Biozentrum and other Basel University institutes. It is tightly integrated in an internationally leading scientific surrounding and contributes to multiple interdisciplinary projects. The position offers a challenging opportunity at a key intersection of rapidly moving areas of research.

Your responsibilities

The successful applicant’s main responsibilities will be to develop, implement, maintain and document proteomics software, data analysis pipelines and informatics infrastructure to enable an automated, standardized data management, analysis, visualization and reporting of the quantitative mass spectrometric data which is generated by the various workflows offered by the PCF. These include global (DIA/SWATH, TMT) and targeted (PRM) mass spectrometric analysis of proteins, modifications, protein/drug interactions and structural constraints. The role further acts as a link of the PCF to the different IT service providers of the University (sciCORE, Research IT and IT Services).


Your profile

Applicants should have a degree in a life science or computational discipline. Excellent skills in R based programming, code documentation and versioning, good understanding of Linux and Windows operating systems and command-line interface as well as prior experience with the analysis of quantitative biological datasets are essential. Experience in the statistical analysis of proteomics data would be advantageous, but is not required. The applicant should embrace a continuous learning mindset and apply scientific rigor following the FAIR principles. In addition, the role requires excellent communication and organization skills, the ability to work well in a team and an advanced knowledge of written and spoken English.


We offer

The position offers a challenging opportunity to join a growing and rapidly evolving bioanalytical field and to join a team of highly motivated scientists. The position is initially for 2 years, with the possibility of further extension for 4 years after positive evaluation. Salary and benefits according to University of Basel standards.


Application / Contact

The application should include a brief personal statement, explaining how your qualifications and experience make you a good candidate for this job, together with a full, up-to-date CV and addresses of 2 references.

We start reviewing applications from 20 August 2024 until the position is filled. In all cases, you will be notified of the outcome of your application. Please note that only online-applications will be accepted.

For further information, please contact Dr. Alexander Schmidt, Head of Proteomics Core Facility, +41 61 207 20 59, alex.schmidt@unibas.ch
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Postdoc in Computational Structural Biology - Evolutionary-scale interpretation of protein functions in human gut microbiome (80-100%)

Start date is by mutual arrangement, with the possibility to start immediately

How does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world’s leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and international research community that has spawned many fundamental discoveries in biology and medicine as well as several Nobel Laureates. Become part of our community!

In Torsten Schwede's group, we use computational methods to model protein structures, analyse protein-ligand interactions, explore the effects of mutations on protein structure and function, and classify protein families on a large-scale. We also explore artificial intelligence to characterise the dark proteome and pioneer automated methods for uncovering unknown protein functions.

Within the SIB Swiss Institute of Bioinformatics, we develop SWISS-MODEL (https://swissmodel.expasy.org), a widely used web-based platform for generating high-accuracy 3D models of protein structures and complexes for application in life sciences. We also develop the Protein Universe Atlas, a web resource designed to streamline the navigation through the extensive wealth of publicly available protein sequence and structure information.

Your position

The Schwede group is seeking a postdoctoral researcher to join the team for an exciting project funded by the Swiss National Science Foundation (SNSF). This project aims to construct an integrative view of putative molecular functions and biological roles of proteins from the human gut microbiome, https://data.snf.ch/grants/grant/220141.

The research will involve an in-depth study of the evolutionary origins and biochemical pathways that underpin the unique role of these proteins in the human gut, using protein evolution and structural bioinformatics approaches. The generated hypotheses will guide experimental validation efforts.

The research is integral to the Protein Universe Atlas project, involving active collaboration with computational and experimental groups, primarily with Dr. Tomasz Kosciółek at Sano Center for Computational Medicine in Kraków, Poland.


Your profile

  • PhD in structural bioinformatics, computational chemistry, computational biology, or related disciplines with a strong publication record
  • You can strengthen our team in at least one of the following areas: protein bioinformatics, protein evolution, metagenomics, data science
  • Experience and interest in modern data analytics techniques and AI / ML would be highly appreciated
  • Good communication skills in English
  • Self-motivation, drive and ability to define new research directions

We offer

The position is funded for 3 years. Our team and the interactive, highly innovative nature of the Biozentrum and of Life Science in Basel provide a stimulating environment that offers all the possibilities to be creative and highly productive. Basel is a city that provides a high standard of living and offers all the advantages of an international community.


Application / Contact

Please apply online and provide a motivation statement that describes how your background and scientific interests match the criteria for this position, CV, and contact information for two references.

Review of applications will begin immediately and proceed until the position has been filled. Early application is strongly encouraged.

For any informal enquiries, please contact: joana.pereira@unibas.ch
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International PhD Program "Biozentrum PhD Fellowships" Winter Call 2024_25

Excellent students from all over the world are encouraged to apply for the prestigious "Biozentrum PhD Fellowships" program. The aim of the fellowships which are sponsored by the Werner Siemens-Foundation and the University of Basel is to select and promote highly talented graduate students in the area of Life Sciences. The fellowships offer direct access to the PhD program of the Biozentrum, University of Basel, additional financial support, a rotation-based selection of the research group, and support for the attendance of scientific meetings and courses during the PhD.
Apply now